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Antigenic Specificity | TLR8 (T |
Clone | [44B05] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: The Toll-like receptor (TLR) family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essential for Toll-induced signal transduction. TLR1 contains an extracellular domain consisting of several leucine-rich regions along with a single cytoplasmic Toll/IL-1R-like domain. TLR2 and TLR4 are activated in response to lipopolysacchride (LPS) stimulation, which results in the activation and translocation of NFkB and smuggests that these receptors are involved in mediating inflammatory responses. TLR6 is highly homologous to TLR1, and like other members of TLR family, it induces NFkB signaling upon activation. TLR8 gene contains three exons, two of which have coding function. Expression of TLR recep |
Immunogen | Immunogen: Recombinant human TLR8 |
Other Names | [LR8; TLR8; CD288; CD 288; MGC119599; # MGC119600], [TLR8; TLR8; CD288] |
Gene, Accession # | [TLR8], Gene ID: 51311, NCBI: NP_619542 |
Catalog # | MBS840140 |
Price | $395 |
Order / More Info | TLR8 (T Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |