VAV1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | VAV1 |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: VAV1 antibody detects endogenous levels of total VAV1. Description: The protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication.Function: Couples tyrosine kinase signals with the activation of the Rho/Rac GTP |
| Immunogen | Immunogen: Purified recombinant fragment of human VAV1 expressed in E. Coli Subcellular Location: Cytoplasmic and Plasma Membrane VAV1, Cytoplasm-VAV2 & VAV3 Tissue Specificity: Widely expressed in hematopoietic cells but not in other cell types. |
| Other Names | [Oncogene vav; p95Vav; Proto-oncogene vav; Protooncogene vav; VAV 1; VAV 1 oncogene; VAV; Vav proto oncogene; VAV_HUMAN; VAV1] |
| Gene, Accession # | [VAV1], Gene ID: 7409, NCBI: NP_001245136.1, UniProt: P15498 |
| Catalog # | MBS9602614 |
| Price | $235, $295, $370 |
| Order / More Info | VAV1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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