Chapsyn-110 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Chapsyn-110 |
| Clone | [S18-30] |
| Host Species | Mouse |
| Reactive Species | human (weak), mouse, rat |
| Isotype | IgG1 |
| Format | fluorescein (FITC) conjugate |
| Size | 0.1 mg |
| Concentration | 1mg/mL |
| Applications | Western (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background Info: Detects ~110kDa. No cross-reactivity against other MAGUK family members, PSD95, SAP97, SAP102, expressed in transfected cells. Scientific Background: Chapsyn-110, is a part of the membrane-associated putative guanylate kinase (MAGUK) family. It binds directly to the NMDA receptor, and Shaker K channel subunits, and is 70-80% identical to PSD-95/SAP90 and SAP97 (1). It associated tightly with the postsynaptic density I brain, and mediates the clustering of both NMDA recpetors and K channels in heterologous cells. The encoded protein forms a heterodimer with PSD-95 that may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins (1, 2). |
| Immunogen | n/a |
| Other Names | [PSD93; Chapsyn-110; MGC131811; PSD-93; Discs Large Homolog 2; DLG2; Postsynaptic density protein PSD-93; DLGH2; Channel-associated protein of synapse-110], [Dlg2; Dlg2; Dlgh2; Dlgh2; Chapsyn-110] |
| Gene, Accession # | Gene ID: 64053, NCBI: NP_071618.1, UniProt: Q63622 |
| Catalog # | MBS800438 |
| Price | $430 |
| Order / More Info | Chapsyn-110 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Kim E., et al. (1996) Neuron. 17:103-113. 2. Godreau D., Neyroud N., Vranckx R. and Hatem S. (2004) Med Sci (Paris). 20(1): 84-88. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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