Phospho-CREB1-S133 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-CREB1-S133
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionCREB1 is a transcription factor that is a member of the bZIP family of DNA binding proteins. It binds as a homodimer to the CRE (cAMP-Responsive Element), an octameric palindrome containing a conserved core sequence, 5-prime-TGACG-3-prime. It consists of two transcript variants encoding respective isoforms produced by alternate splicing. It is mapped to 2q32.3-q34. It is phosphorylated by several protein kinases and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. CREB1 is crucial for the consolidation of long-term conditioned fear memories, but not for encoding, storage, or retrieval of these memories. It is required for the stability of reactivated or retrieved conditioned fear memories.
ImmunogenImmunogen: A phospho specific peptide corresponding to residues surrounding S133 of human CREB1 Calculated Molecular Weight: 43kDa
Other Names[Phospho-CREB1-S133: CREB-1; CREB1], [CREB1; CREB1; CREB; CREB-1; cAMP-responsive element-binding protein 1]
Gene, Accession #[CREB1], Gene ID: 1385, NCBI: P16220.2, UniProt: P16220
Catalog #MBS128455
Price$235, $350, $525
Order / More InfoPhospho-CREB1-S133 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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