Alpha-Catenin, Human Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAlpha-Catenin, Human
Clone1G5
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB)
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DescriptionProduct Description: The monoclonal antibody 1G5 reacts with human alpha-catenin. Alpha-catenin belongs together with beta- and gamma-catenin to the catenin family. Catenins comprise a large family of Ca2 -dependent, homotypic cell-cell adhesion molecules that play important roles in development, epithelial cell polarity and tumor progression. Cadherins are single pass, type I transmembrane proteins that are localized in the adherens junction. To be fully functional, the cadherin cytoplasmic domain must be linked to the actin cytoskeleton through a group of proteins termed catenins: alpha-catenin, beta-catenin and plakoglobin. Alpha catenin interacts with the cadherin indirectly via interactions with beta-catenin or plakoglobin.
Immunogenn/a
Other Names[alpha-catenin, partial; Catenin alpha-1; catenin alpha-1; alpha-catenin; alphaE-catenin; alpha E-catenin; alpha-E-catenin; renal carcinoma antigen NY-REN-13; cadherin-associated protein,102kDa; catenin (cadherin-associated protein), alpha 1, 102kDa; Alpha E-catenin; Cadherin-associated protein; Renal carcinoma antigen NY-REN-13], [CTNNA1; CTNNA1; CAP102]
Gene, Accession #Gene ID: 1495, NCBI: AAA35502.1
Catalog #MBS584337
Price$520
Order / More InfoAlpha-Catenin, Human Antibody from MYBIOSOURCE INC.
Product Specific References1. Nieman, M et al; Mechanism of extracellular domain-deleted dominant negative cadherins. J Cell Science 1999, 112: 1621 2. Johnson, K et al; P- and E-cadherin are in separate complexes in cells expressing both cadherins. Exp Cell Res 1993, 207: 252
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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