LC3 (APG8A) (D106), 91-117 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | LC3 (APG8A) (D106), 91-117 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: bovine, mouse, rat) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.33 |
| Applications | Immunofluorescence (IF), ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This LC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-117 amino acids from human LC3. Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). MAP1A and MAP1B are microtubule-associated p |
| Immunogen | n/a |
| Other Names | [Microtubule-associated proteins 1A/1B light chain 3A; Autophagy-related protein LC3 A; Autophagy-related ubiquitin-like modifier LC3 A; MAP1 light chain 3-like protein 1; MAP1A/MAP1B light chain 3 A; MAP1A/MAP1B LC3 A; Microtubule-associated protein 1 light chain 3 alpha; MAP1LC3A] |
| Gene, Accession # | [MAP1LC3A], Gene ID: 84557, NCBI: NP_115903.1, UniProt: Q9H492 |
| Catalog # | MBS9201691 |
| Price | $165, $370 |
| Order / More Info | LC3 (APG8A) (D106), 91-117 Antibody from MYBIOSOURCE INC. |
| Product Specific References | References for protein: 1.Tanida, I., et al., J. Biol. Chem. 279(35):36268-36276 (2004). 2.He, H., et al., J. Biol. Chem. 278(31):29278-29287 (2003). 3.Mann, S.S., et al., J. Neurosci. Res. 43(5):535-544 (1996). References for U251 cell line: 1. Westermark B.; Ponten J.; Hugosson R. (1973). Determinants for the establishment of permanent tissue culture lines from human gliomas. Acta Pathol Microbiol Scand A. 81:791-805. [PMID: 4359449]. 2. Ponten, J.,Westermark B. (1978). Properties of Human Malignant Glioma Cells in Vitro. Medical Biology 56: 184-193.[PMID: 359950]. 3. Geng Y.;Kohli L.; Klocke B.J.; Roth K.A.(2010). Chloroquine-induced autophagic vacuole accumulation and cell death in glioma cells is p53 independent. Neuro Oncol. 12(5): 473-481.[ PMID: 20406898]. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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