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Antigenic Specificity | CCR1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, monkey |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg |
Concentration | 0.5 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: Chemokines play an important role in inflammation and are critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. One of the CCR receptors, CCR1, is expressed on neutrophils, monocytes, lymphocytes, and eosinophils and binds the leukocyte chemoattractant and hemopoiesis regulator macrophage-inflammatory protein (MIP-1), eotaxin, as well as several other related chemokines. Mice lacking the chemokine receptor CCR1 have defects in neutrophil trafficking and proliferation. |
Immunogen | Immunogen: Synthetic peptide surrounding amino acid 341 of human CCR1 |
Other Names | [CMKBR1; CMKR1; CD191; CKR-1; HM145; MIP1aR; C-C chemokine receptor type 1], [CCR1; CCR1; CKR1; CD191; CKR-1; HM145; CMKBR1; MIP1aR; SCYAR1; CMKBR1; CMKR1; SCYAR1; C-C CKR-1; CC-CKR-1; CCR-1; CCR1; MIP-1alpha-R] |
Gene, Accession # | [CCR1], Gene ID: 1230, NCBI: NP_001286.1, UniProt: P32246 |
Catalog # | MBS841067 |
Price | $150, $330 |
Order / More Info | CCR1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |