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Antigenic Specificity | MRGPRX1 - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against MRGPRX1. It was validated on Western BlotTarget Description: MRGPRX1 is an orphan receptor. MRGPRX1 is probably involved in the function of nociceptive neurons. It may regulate nociceptor function and/or development, including the sensation or modulation of pain. MRGPRX1 is potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. MRGPRX1 is activated by the antimalarial drug, chloroquine and may mediate chloroquine-induced itch, in an histamine-ind |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human MRGPRX1 |
Other Names | [mas-related G-protein coupled receptor member X1; Mas-related G-protein coupled receptor member X1; mas-related G-protein coupled receptor member X1; MAS related GPR family member X1; Sensory neuron-specific G-protein coupled receptor 3/4] |
Gene, Accession # | [MRGPRX1], Gene ID: 259249, NCBI: NP_671732, UniProt: Q96LB2 |
Catalog # | MBS3214572 |
Price | $335 |
Order / More Info | MRGPRX1 - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |