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Antigenic Specificity | gp120 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against 15 amino acids from near the center of gp120. |
Other Names | [HIV-1 glycoprotein 120] |
Gene, Accession # | [gp120], NCBI: AAB05604 |
Catalog # | MBS9400963 |
Price | $320 |
Order / More Info | gp120 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |