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Antigenic Specificity | VDAC1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of various cell lines, using VDAC1 antibody. Immunohistochemistry of paraffin-embedded human stomach cancer using VDAC1 antibody at dilution of 1:200 (400x lens). Immunofluorescence analysis of HeLa cell using VDAC1 antibody. Blue: DAPI for nuclear staining. Voltage-dependent anion channel (VDAC), ubiquitously expressed and located in the outer mitochondrial membrane, is generally thought to be the primary means by which metabolites diffuse in and out of the mitochondria (1). In addition, this channel plays a role in apoptotic signaling. The change in mitochondrial permeability characteristic of apoptosis is mediated by Bcl-2 family proteins, which bind to VDAC, altering the channel kinetics (2 |
Immunogen | Immunogen: Recombinant protein of human VDAC1 |
Other Names | [voltage-dependent anion-selective channel protein 1; Voltage-dependent anion-selective channel protein 1; voltage-dependent anion-selective channel protein 1; voltage dependent anion channel 1; Outer mitochondrial membrane protein porin 1; Plasmalemmal porin; Porin 31HL; Porin 31HM], [VDAC1; VDAC1; PORIN; VDAC-1; VDAC; VDAC-1; hVDAC1] |
Gene, Accession # | [VDAC1], Gene ID: 7416, NCBI: NP_003365.1 |
Catalog # | MBS419466 |
Price | $385 |
Order / More Info | VDAC1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |