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Antigenic Specificity | NIK (Center), 119-148 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This NIK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-148 amino acids from the Central region of human NIK. NIK (mitogen-activated protein kinase kinase kinase 14), a member of the Ser/Thr protein kinase family, binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. |
Immunogen | n/a |
Other Names | [Mitogen-activated protein kinase kinase kinase 14; NF-kappa-beta-inducing kinase; HsNIK; Serine/threonine-protein kinase NIK; MAP3K14; NIK] |
Gene, Accession # | [MAP3K14], Gene ID: 9020, NCBI: NP_003945.2, UniProt: Q99558 |
Catalog # | MBS9201819 |
Price | $165, $370 |
Order / More Info | NIK (Center), 119-148 Antibody from MYBIOSOURCE INC. |
Product Specific References | Andreakos, E., et al., Blood 101(3):983-991 (2003). Ninomiya-Tsuji, J., et al., Nature 398(6724):252-256 (1999). Aronsson, F.C., et al., Hum. Genet. 103(3):340-345 (1998). Lin, X., et al., Mol. Cell. Biol. 18(10):5899-5907 (1998). Malinin, N.L., et al., Nature 385(6616):540-544 (1997). |