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Antigenic Specificity | Caveolin 2 (Phospho-Tyr27) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Caveolin 2 (Phospho-Tyr27) antibody detects endogenous levels of total Caveolin 2 (Phospho-Tyr27). Function: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (By similarity).Subunit Structure: Monomer or |
Immunogen | Immunogen: A synthesized peptide derived from human Caveolin 2 (Phospho-Tyr27) Subcellular Location: Nucleus. Cytoplasm. Golgi Apparatus Membrane. Cell Membrane. Membrane > Caveola. Potential hairpin-like structure in the membrane. Membrane protein of caveolae. Tyr-19-phosphorylated form is enriched at sites of cell-cell contact and is translocated to the nucleus in complex with MAPK1 in response to insulin (By similarity). Tyr-27-phosphorylated form is located both in the cytoplasm and plasma m |
Other Names | [CAV; CAV2; CAV2_HUMAN; Caveolae protein 20 kD; Caveolin 2; Caveolin 2 isoform a and b; Caveolin-2; MGC12294; OTTHUMP00000025032; OTTHUMP00000195982] |
Gene, Accession # | [CAV2], Gene ID: 858, NCBI: NP_001193676.1, UniProt: P51636 |
Catalog # | MBS9601600 |
Price | $240, $280 |
Order / More Info | Caveolin 2 (Phospho-Tyr27) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |