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Antigenic Specificity | Abi-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Abi-1 Polyclonal Antibody detects endogenous levels of Abi-1 protein. ABI1 encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein (abl interactor 1) plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t (10;11) chromosomal translocation involving this |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human Abi-1 |
Other Names | [Rabbit Abi-1; ABI1; SSH3BP1; Abl interactor 1; Abelson interactor 1; Abi-1; Abl-binding protein 4; AblBP4; Eps8 SH3 domain-binding protein; Eps8-binding protein; Nap1-binding protein; Nap1BP; Spectrin SH3 domain-binding protein 1; e3B1] |
Gene, Accession # | [Abi-1], Gene ID: 10006, NCBI: Q8IZP0.4, UniProt: Q8IZP0 |
Catalog # | MBS9701314 |
Price | $130, $220, $325 |
Order / More Info | Abi-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |