Mismatch Repair Antibody Sampler Kit Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMismatch Repair Antibody Sampler Kit
Clonen/a
Host Speciesn/a
Reactive Speciesn/a
Isotypen/a
Formatunconjugated
Size1 kit
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionBackground: The DNA mismatch repair system (MMR) repairs post-replication DNA, inhibits recombination between nonidentical DNA sequences, and induces both checkpoint and apoptotic responses following certain types of DNA damage. MSH2 (MutS homologue 2) forms the hMutS-alpha dimer with MSH6 and is an essential component of the mismatch repair process. hMutS-alpha is part of the BRCA1-associated surveillance complex (BASC), a complex that also contains BRCA1, MLH1, ATM, BLM, PMS2 proteins, and the Rad50-Mre11-NBS1 complex. Mutations in MSH6 and other MMR proteins have been found in a large proportion of hereditary nonpolyposis colorectal cancer (Lynch Syndrome), the most common form of inherited colorectal cancer in the Western world. Mutatio
Immunogenn/a
Other Namesn/a
Gene, Accession #n/a
Catalog #MBS2550149
Price$265
Order / More InfoMismatch Repair Antibody Sampler Kit Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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