RPA2 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-RPA2 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | RPA2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | RPA70 (HSSB, REPA1, RF-A, RP-A, p70) is a component of a heterotrimeric complex, composed of 70, 32/30 and 14 kDa subunits, collectively known as RPA. RPA is a single stranded DNA binding protein, whose DNA binding activity is believed to reside entirely in the 70 kDa subunit. The complex is required for almost all aspects of cellular DNA metabolism such as DNA replication (1-3), recombination, cell cycle and DNA damage checkpoints, and all major types of DNA repair including nucleotide excision, base excision, mismatch and double-strand break repairs (4-7). In response to genotoxic stress in eukaryotic cells, RPA has been shown to associate with the Rad9/Rad1/Hus1 (9-1-1) checkpoint complex (8). RPA is hyperphosphorylated upon DNA damage o |
| Immunogen | Immunogen: Recombinant protein of human RPA2 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [REPA2; RPA32] |
| Gene, Accession # | [RPA2], Gene ID: 6118, NCBI: NP_001273005.1, UniProt: P15927 |
| Catalog # | MBS8501250 |
| Price | $310 |
| Order / More Info | RPA2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Liu, V.F. and Weaver, D.T. (1993) Mol. Cell Biol. 13, 7222-7231. 2. Wobbe, C.R. et al. (1987) Proc. Natl. Acad. Sci. USA 84, 1834-1838. 3. Fairman, M.P. and Stillman, B. (1988) EMBO J. 7, 1211-1218. 4. Wold, M.S. and Kelly, T. (1988) Proc. Natl. Acad. Sci. USA 85, 2523-2527. 5. Zhou, B.B. and Elledge, S.J. (2000) Nature 408, 433-439. 6. Kastan, M.B. and Bartek, J. (2004) Nature 432, 316-323. 7. Sancar, A. et al. (2004) Annu. Rev. Biochem. 73, 39-85. 8. Guo, S. et al. (2006) J Biol Chem 281, 21607-16. 9. Wu, X. et al. (2005) Oncogene 24, 4728-4735. 10. Binz, S.K. et al. DNA Repair (Amst) 3, 1015-1024. 11. Nuss, J.E. et al. (2005) Biochemistry 44, 8428-8437. 12. Yuzhakov, A. et al. (1999) EMBO J. 18, 6189-6199. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies