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Antigenic Specificity | HDAC4/HDAC5/HDAC9 (Ab-246/259/220) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total HDAC4/HDAC5/HDAC9 protein. Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around aa.244~248/257~261/218~222 (T-A-S-E-P) derived from Human HDAC4/HDAC5/HDAC9. |
Other Names | [HD4/HD5/HD9] |
Gene, Accession # | [HDAC4/HDAC5/HDAC9], Gene ID: 9759, NCBI: NP_006028.2, UniProt: P56524 |
Catalog # | MBS9401190 |
Price | $200, $255 |
Order / More Info | HDAC4/HDAC5/HDAC9 (Ab-246/259/220) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |