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Antigenic Specificity | SIRT1 |
Clone | polyclonal |
Host Species | Chicken |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SIRT1 Antibody: The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT1 has the closest homology to the yeast Sir2p and is widely expressed in fetal and adult tissues. SIRT1 regulates the p53-dependent DNA damage response pathway by binding to and deacetylatin |
Immunogen | Immunogen: SIRT1 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human SIRT1. Buffer: SIRT1 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [SIRT1; SIR2L1; SIR2L1; NAD-dependent protein deacetylase sirtuin-1; Regulatory protein SIR2 homolog 1; hSIRT1; sirtuin 1], [SIRT1; SIRT1; SIR2L1; SIR2L1; hSIRT1; hSIR2; 75SirT1] |
Gene, Accession # | [SIRT1], Gene ID: 23411, NCBI: NP_036370, UniProt: Q96EB6 |
Catalog # | MBS151072 |
Price | $375 |
Order / More Info | SIRT1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |