DOG1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-DOG1 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | DOG1 |
| Clone | [RBT-DOG1] |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | IgG |
| Format | unconjugated |
| Size | 5 Control Slides, 3 ml (Prediluted), 0.1 mL (Concentrate) |
| Concentration | n/a |
| Applications | n/a |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | DOG1 (discovered on GIST 1), a cell-surface protein of unknown function, is expressed strongly on the cell surface of GISTs and is rarely expressed in other soft tissue tumors. Among GIST cases with c-Kit mutations, the DOG1 antibody identified 11% more cases than a c-Kit antibody. DOG1 identifies the vast majority of both c-Kit negative and PDGFRA mutated GIST cases that may still benefit from imatinib mesylate (Gleevac), an inhibitor of the kit tyrosine kinase. In addition, DOG1 immunoreactivity is seen in fewer cases of mesenchymal and epithelial tumors, and melanomas when compared with c-Kit. The use of this highly-sensitive and specific novel marker should increase the accuracy of GIST diagnosis. |
| Immunogen | n/a |
| Other Names | n/a |
| Gene, Accession # | [DOG1] |
| Catalog # | MBS370152 |
| Price | $130, $215, $230 |
| Order / More Info | DOG1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.