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Antigenic Specificity | CD11b |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total CD11b protein. This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant fragment corresponding to a region within amino acids 611 and 1042 of CD11b. |
Other Names | [CD11B; CR3A; MAC-1; MAC1A; MGC117044; MO1A; SLEB6; ITGAM; cell surface glycoprotein MAC-1 subunit alpha; macrophage antigen alpha polypeptide; leukocyte adhesion rec] |
Gene, Accession # | [CD11b], Gene ID: 3684, NCBI: NP_000623.2, UniProt: P11215 |
Catalog # | MBS9408055 |
Price | $320 |
Order / More Info | CD11b Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |