Phospho-PDPK1 (S396) Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Phospho-PDPK1 (S396) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.4 |
| Applications | Dot Blot (DB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This PDPK1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S396 of human PDPK1. PDPK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDPK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDPK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase, and the stimulation of glycogen synthesis. Because of the role that PDPK1 plays in insulin-induced glyco |
| Immunogen | n/a |
| Other Names | [3-phosphoinositide-dependent protein kinase 1; hPDK1; PDPK1; PDK1] |
| Gene, Accession # | [PDPK1], Gene ID: 5170, NCBI: NP_001248745.1, UniProt: O15530 |
| Catalog # | MBS9214216 |
| Price | $165, $370 |
| Order / More Info | Phospho-PDPK1 (S396) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Nilsen, T., et al., J. Biol. Chem. 279(6):4794-4801 (2004). Collins, B.J., et al., EMBO J. 22(16):4202-4211 (2003). Egawa, K., et al., J. Biol. Chem. 277(41):38863-38869 (2002). Sato, S., et al., J. Biol. Chem. 277(42):39360-39367 (2002). Scott, M.T., et al., EMBO J. 21(24):6771-6780 (2002). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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