Nestin (Cancer Stem Cell Marker) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Nestin (Cancer Stem Cell Marker) |
| Clone | [NES/2911] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG |
| Format | purified |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Nestin is a major intermediate filament (IF) protein of embryonic central nervous system progenitor cells. It is also a component of the dynamic IF network during muscle development, where it polymerizes with Desmin and Vimentin. Nestin co-assembles with Vimentin or -internexin and forms heterodimer coiled-coil molecules which then further assemble into 10 nml IFs. Deletion of the IF consensus rod domain in nestin alters nestin localization in CNS precursor cells and radial glial cells in vivo. Nestin is a marker for neuroepithelial stem cells, glioma cells and tumor endothelial cells during rapid growth. During axon elongation of differentiation neurons, nestin localizes to the growth cones and may play a role in growth cone g |
| Immunogen | Immunogen: Recombinant human NES protein fragment around aa 698-844 (exact sequence is proprietary) |
| Other Names | [ESTM 46; FLJ21841; Intermediate filament protein; Nbla00170; nes] |
| Gene, Accession # | [NES], Gene ID: 10763, NCBI: P48681.2, UniProt: P48681 |
| Catalog # | MBS4380786 |
| Price | $190, $340, $340 |
| Order / More Info | Nestin (Cancer Stem Cell Marker) Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Yamahatsu, K., et al. (2012). International Journal of Oncology, 40, 1345-1357. 2. Zhang Y, et al. Nat Commun. 2018 Sep 6;9(1):3613 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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