Human PARP Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Human PARP antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Human PARP |
| Clone | polyclonal |
| Host Species | Mouse |
| Reactive Species | human, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PARP, a 116 kDa nuclear poly (ADPribose) polymerase, appears to be involved in DNA repair in response to environmental stress (1). This protein can be cleaved by many ICElike caspases in vitro (2,3) and is one of the main cleavage targets of caspase3 in vivo (4,5). In human PARP, the cleavage occurs between Asp214 and Gly215, which separates the PARP aminoterminal DNA binding domain (24 kDa) from the carboxyterminal catalytic domain (89 kDa) (2,4). PARP helps cells to maintain their viability; cleavage of PARP facilitates cellular disassembly and serves as a marker of cells undergoing apoptosis (6). |
| Immunogen | Immunogen: Synthetic peptide of human PARP, conjugated to KLH. |
| Other Names | [PARP Mouse Mab], [PARP1; PARP; PPOL; ADPRT; ADPRT1; PARP1; ADPRT 1; pADPRT1] |
| Gene, Accession # | [PARP] |
| Catalog # | MBS125979 |
| Price | $200, $275, $430 |
| Order / More Info | Human PARP Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Satoh, M.S. and Lindahl, T. (1992) Nature 356, 356358.2. Lazebnik, Y. A. et al. (1994) Nature 371, 346347.3. Cohen, G.M. (1997) Biochem. J. 326, 116.4. Nicholson, D. W. et al. (1995) Nature 376, 3743.5. Tewari, M. et al. (1995) Cell 81, 801809. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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