NME1/nm23-H1/NDPK-A (Suppressor of Metastasis) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNME1/nm23-H1/NDPK-A (Suppressor of Metastasis)
Clone[CPTC-NME1-2]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2a, kappa
Formatpurified
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThe nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP-K). In humans, NDP kinase A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human C-Myc promotor.
ImmunogenImmunogen: Recombinant full-length human NME1 protein
Other Names[AWD; GAAD; Granzyme A activated DNase; Metastasis inhibition factor NM23; NB; NBS; NDP kinase A; NM23 long variant; included; NM23H1B; NME/NM23 nucleoside diphosphate kinase 1; NME1-NME2 spliced read-through transcript; included; Non-metastatic protein 23; homolog 1; Nucleoside diphosphate kinase A; Tumor metastatic process-associated protein]
Gene, Accession #[NME1], Gene ID: 4830, NCBI: NP_000260.1, UniProt: P15531
Catalog #MBS4381120
Price$190, $340, $340
Order / More InfoNME1/nm23-H1/NDPK-A (Suppressor of Metastasis) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesSteeg, P.S., et al. 1988. J. Natl. Cancer Inst. 80: 200-209
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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