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Antigenic Specificity | ECD - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Regulator of p53/TP53 stability and function. Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP. May be involved transcriptional regulation. In vitro has intrinsic transactivation activity enhanced by EP300. May be a transcriptional activator required for the expression of glycolytic genes. Involved in regulation of cell cycle progression. Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins. The cell cycle -regulating function may depend on its RUVBL1-mediated association with the R2TP complex. May play a role in regulation of pre-mRNA splicing. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ECD |
Other Names | [protein ecdysoneless homolog isoform 2; Protein SGT1; protein ecdysoneless homolog; ecdysoneless cell cycle regulator; Protein ecdysoneless homolog; Suppressor of GCR2] |
Gene, Accession # | [ECD], Gene ID: 11319, NCBI: NP_001129224.1, UniProt: O95905 |
Catalog # | MBS3223455 |
Price | $335 |
Order / More Info | ECD - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |