ECD - middle region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityECD - middle region
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionRegulator of p53/TP53 stability and function. Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP. May be involved transcriptional regulation. In vitro has intrinsic transactivation activity enhanced by EP300. May be a transcriptional activator required for the expression of glycolytic genes. Involved in regulation of cell cycle progression. Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins. The cell cycle -regulating function may depend on its RUVBL1-mediated association with the R2TP complex. May play a role in regulation of pre-mRNA splicing.
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the middle region of human ECD
Other Names[protein ecdysoneless homolog isoform 2; Protein SGT1; protein ecdysoneless homolog; ecdysoneless cell cycle regulator; Protein ecdysoneless homolog; Suppressor of GCR2]
Gene, Accession #[ECD], Gene ID: 11319, NCBI: NP_001129224.1, UniProt: O95905
Catalog #MBS3223455
Price$335
Order / More InfoECD - middle region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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