MEK2 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | MEK2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit polyclonal to Human MEK2. MEK1 and MEK2, also called MAPK or Erk kinases, are dual-specificity protein kinases that function in a mitogen activated protein kinase cascade controlling cell growth and differentiation (1-3). Activation of MEK1 and MEK2 occurs through phosphorylation of two serine residues at positions 217 and 221, located in the activation loop of subdomain VIII, by Raf-like molecules. MEK1/2 is activated by a wide variety of growth factors and cytokines and also by membrane depolarization and calcium influx (1-4). Constitutively active forms of MEK1/2 are sufficient for the transformation of NIH/3T3 cells or the differentiation of PC-12 cells (4). MEK activates p44 and p42 MAP kinase by phosphorylating both threonine a |
| Immunogen | Immunogen: A Fusion protein of human MEK2 |
| Other Names | [MAP2K2; MAP2K2; FLJ26075; MAPKK2; MEK2; MKK2; PRKMK2], [MAP2K2; MAP2K2; CFC4; MEK2; MKK2; MAPKK2; PRKMK2; MEK2; MKK2; PRKMK2; MAP kinase kinase 2; MAPKK 2; MEK 2] |
| Gene, Accession # | Gene ID: 5605, NCBI: NP_109587.1, UniProt: P36507 |
| Catalog # | MBS125848 |
| Price | $275, $430 |
| Order / More Info | MEK2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Crews, C.M. et al. (1992) Science 258, 478-480. 2. Alessi, D.R. et al. (1994) EMBO J. 13, 1610-1619. 3. Rosen, L.B. et al. (1994) Neuron 12, 1207-1221. 4. Cowley, S. et al. (1994) Cell 77, 841-852. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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