alphaT- Catenin Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-alphaT- Catenin antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | alphaT- Catenin |
| Clone | [892_24D2S] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC), Immunocytochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: 892_24D2S reacts with an epitope loCated between residues 164-177 of the Human alphaT-Catenin protein. Catenins are proteins that connect cadherin/beta-Catenin cell adhesion complexes to the actin cytoskeleton. Although originally discovered in testis, alphaT-Catenin is expressed in other tissues, the highest levels being observed in heart. Immunohistochemical analysis showed Human alphaT-Catenin localization at intercalated discs of cardiomyocytes and in peritubular myoid cells of testis. It is proven that alphaT-Catenin can functionally restore cell-cell adhesion in colon cancer cells lacking alpha-Catenins. This indiCates that this protein is involved in the formation of specific cell-cell contacts in specific types of muscl |
| Immunogen | Source Note: 892_24D2S is a Mouse monoclonal IgG2a antibody derived by fusion of SP2/0-Ag14 Mouse myeloma cells with spleen cells from a C57Bl/6 Mouse immunized with a synthetic peptide corresponding to amino acids 164-177 of the Human alphaT-Catenin protein including an additional N-terminal cysteine (CVANKSDLQKTYQKL) coupled to keyhole limpet hemocyanin. |
| Other Names | [alphaT-catenin; Catenin alpha-3; catenin alpha-3; alpha T-catenin; alpha-T-catenin; alpha-catenin-like protein; cadherin-associated protein; catenin (cadherin-associated protein), alpha 3; Alpha T-catenin; Cadherin-associated protein], [CTNNA3; CTNNA3; VR22] |
| Gene, Accession # | Gene ID: 29119, NCBI: AAF21801.1, UniProt: Q9UI47 |
| Catalog # | MBS570076 |
| Price | $415 |
| Order / More Info | alphaT- Catenin Antibody from MYBIOSOURCE INC. |
| Product Specific References | Janssens, B., Goossens, S., Staes, K., Gilbert, B., van Hengel, J., Colpaert, C., Bruyneel, E., Mareel, M., and van Roy, F. (2001). alphaT-Catenin: a novel tissue-specific beta-Catenin-binding protein mediating strong cell-cell adhesion, J. Cell. Sci. 114, 3177-88. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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