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Antigenic Specificity | Mouse Sike1 (N-term), 36-63 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse (predicted reactivity: rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.38 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Mouse Sike1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-63 amino acids from the N-terminal region of mouse Sike1. Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus-and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways (By similarity). |
Immunogen | n/a |
Other Names | [Suppressor of IKBKE 1; Suppressor of IKK-epsilon; Sike1] |
Gene, Accession # | [Sike1], Gene ID: 66641, NCBI: NP_079955.1, UniProt: Q9CPR7 |
Catalog # | MBS9212089 |
Price | $165, $370 |
Order / More Info | Mouse Sike1 (N-term), 36-63 Antibody from MYBIOSOURCE INC. |
Product Specific References | Katayama, S., et al. Science 309(5740):1564-1566(2005) Carninci, P., et al. Science 309(5740):1559-1563(2005) |