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Antigenic Specificity | MTBP |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG |
Format | ascites |
Size | 0.1 mL |
Concentration | 1ug/ul |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody is directed against human MTBP protein. The product was produced from clarified mouse ascetic fluid. A BLAST analysis was used to suggest reactivity with this protein from human (100% homology) and chimpanzee. Cross reactivity with MTBP protein from mouse (77% homology) and chicken (79% homology) is unlikely due to the relatively low number of positive residues and high number of gaps within this sequence. Cross reactivity with MTBP homologues from other sources has not been determined. The MDM2 onco-protein is over expressed in human cancer cells and it promotes tumorigenesis by directly blocking the function of the p53 tumor suppressor. Studies also indicate that MDM2 regulates cell proliferation via p53 independent mechanis |
Immunogen | Immunogen: This protein A purified monoclonal antibody was produced by repeated immunizations with a recombinant amino-terminal HIS6X-tagged polypeptide corresponding to amino acid residues 667-812 of human MTBP protein. |
Other Names | n/a |
Gene, Accession # | [MTBP] |
Catalog # | MBS4157845 |
Price | $540 |
Order / More Info | MTBP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |