Toll-like Receptor Adaptor Protein (TIRP) (CT) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityToll-like Receptor Adaptor Protein (TIRP) (CT)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunoaffinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin
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DescriptionTIRP is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs) (1-3). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses (4). TIRP, along with other molecules such as TRIF, MAL, and MyD88, serves as an adaptor protein that allows for the interaction and activation of the IL-1R-associated kinase (IRAK) family, the subsequent activation of TNF receptor associated factor (TRAF)-6, and ultimately the activation of NF-?B (5). Expression of TIRP appears to be essential for TLR4 signalling (6).
ImmunogenImmunogen: Rabbit polyclonal TIRP antibody was raised against a peptide corresponding to amino acids at the C-terminus of human TIRP.
Other Names[TICAM2 protein; TIRAP3a; TIR-containing adapter molecule-2; Putative NFkB activating protein], [TMED7-TICAM2; TICAM2; TAG; TIRAP3; TIRP; TRAM; TICAM-2; MyD88-4]
Gene, Accession #[TIRP], Gene ID: 100302736, NCBI: NP_001157941.1, UniProt: Q86XR7
Catalog #MBS395875
Price$405
Order / More InfoToll-like Receptor Adaptor Protein (TIRP) (CT) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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