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Antigenic Specificity | Toll-like Receptor Adaptor Protein (TIRP) (CT) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TIRP is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs) (1-3). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses (4). TIRP, along with other molecules such as TRIF, MAL, and MyD88, serves as an adaptor protein that allows for the interaction and activation of the IL-1R-associated kinase (IRAK) family, the subsequent activation of TNF receptor associated factor (TRAF)-6, and ultimately the activation of NF-?B (5). Expression of TIRP appears to be essential for TLR4 signalling (6). |
Immunogen | Immunogen: Rabbit polyclonal TIRP antibody was raised against a peptide corresponding to amino acids at the C-terminus of human TIRP. |
Other Names | [TICAM2 protein; TIRAP3a; TIR-containing adapter molecule-2; Putative NFkB activating protein], [TMED7-TICAM2; TICAM2; TAG; TIRAP3; TIRP; TRAM; TICAM-2; MyD88-4] |
Gene, Accession # | [TIRP], Gene ID: 100302736, NCBI: NP_001157941.1, UniProt: Q86XR7 |
Catalog # | MBS395875 |
Price | $405 |
Order / More Info | Toll-like Receptor Adaptor Protein (TIRP) (CT) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |