FASL Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFASL
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesn/a
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunocytochemistry (ICC)
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DescriptionFas and Fas Ligand (FASL) belong to the TNF superfamily and are type I and type II transmembrane proteins, respectively. Binding of FASL to Fas triggers apoptosis in Fas-bearing cells. The mechanism of apoptosis involves recruitment of pro-caspase 8 through an adaptor molecule called FADD followed by processing of the pro-enzyme to active forms. These active caspases then cleave various cellular substrates leading to the eventual cell death. sFasR is capable of inhibiting FASL-induced apoptosis by acting as a decoy receptor that serves as a sink for FASL.
ImmunogenImmunogen: FASL antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of human FAS-L, different from the related Rabbit sequence by two amino acids, and from the related rat sequence by three amino acids, as the immunogen
Other Names[Affinity Purified Goat FASL; FASL; FASL; TNFSF6; sFASL; Apo I Ligand; CD95L; APTL; soluble Fas Ligand]
Gene, Accession #[FASL], Gene ID: 102178753
Catalog #MBS5312585
Price$345
Order / More InfoFASL Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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