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Antigenic Specificity | CADPS2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CADPS2 antibody detects endogenous levels of total CADPS2. Function: Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles. Regulates neurotrophin release from granule cells leading to regulate cell differentiation and survival during cerebellar development. May specifically mediate the Ca2+-dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles (By similarity).Subunit Structure: Homodimer (By similarity). Interacts with the dopamine receptor DRD2.Similarity: The PH domain is essential for regulated exocytosis and binds phospholipids. |
Immunogen | Immunogen: A synthesized peptide derived from human CADPS2 Subcellular Location: Cytoplasmic. Membrane-associated to vesicles. Tissue Specificity: Widely expressed. Expressed in all adult and fetal tissues examined, with the strongest expression in kidney and pancreas. In brain, it is expressed at high levels in cerebellum, to a lesser degree in cerebral cortex, occipital pole, and frontal and temporal lobes. Only weakly expressed in medulla, spinal cord and putamen. Predicted Cross Reactivity: |
Other Names | [Cadps2; Calcium-dependent activator protein for secretion 2; Calcium-dependent secretion activator 2; CAPS2; KIAA1591] |
Gene, Accession # | [CADPS2], Gene ID: 93664, NCBI: NP_001009571.2, UniProt: Q86UW7 |
Catalog # | MBS9609628 |
Price | $240, $280 |
Order / More Info | CADPS2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |