Phospho-E-Catenin (Ser655/Thr658) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-E-Catenin (Ser655/Thr658)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: Phospho-E-Catenin (Ser655/Thr658) antibody detects endogenous levels of E-Catenin only when phosphorylated at Ser655/Thr658. Function: Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E-and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bin
ImmunogenImmunogen: A synthesized peptide derived from human Phospho-E-Catenin (Ser655/Thr658) Subcellular Location: Cell Membrane and Cytoplasm > Cytoskeleton. Cell Junction > Adherens Junction. Cell Membrane. Cell Junction. Found at cell-cell boundaries and probably at cell-matrix boundaries. Tissue Specificity: Expressed ubiquitously in normal tissues.
Other Names[Alpha E-catenin; Cadherin associated protein 102kDa; Cadherin associated protein; Cadherin-associated protein; CAP 102; CAP102; Catenin (cadherin associated protein) alpha 1 102kDa; Catenin (cadherin associated protein), alpha 1, 102kDa; Catenin alpha 1; Catenin alpha-1; CTNA1_HUMAN; CTNNA 1; Ctnna1; FLJ36832; FLJ52416; MDPT2; NY REN 13 antigen; OTTHUMP00000224141; OTTHUMP00000224147; Renal carcinoma antigen NY REN 13; Renal carcinoma antigen NY-REN-13]
Gene, Accession #[CTNNA1], Gene ID: 1495, NCBI: NP_001277236.1, UniProt: P35221
Catalog #MBS9604448
Price$240, $280
Order / More InfoPhospho-E-Catenin (Ser655/Thr658) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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