Edit |   |
---|---|
Antigenic Specificity | Phospho-E-Catenin (Ser655/Thr658) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-E-Catenin (Ser655/Thr658) antibody detects endogenous levels of E-Catenin only when phosphorylated at Ser655/Thr658. Function: Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E-and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bin |
Immunogen | Immunogen: A synthesized peptide derived from human Phospho-E-Catenin (Ser655/Thr658) Subcellular Location: Cell Membrane and Cytoplasm > Cytoskeleton. Cell Junction > Adherens Junction. Cell Membrane. Cell Junction. Found at cell-cell boundaries and probably at cell-matrix boundaries. Tissue Specificity: Expressed ubiquitously in normal tissues. |
Other Names | [Alpha E-catenin; Cadherin associated protein 102kDa; Cadherin associated protein; Cadherin-associated protein; CAP 102; CAP102; Catenin (cadherin associated protein) alpha 1 102kDa; Catenin (cadherin associated protein), alpha 1, 102kDa; Catenin alpha 1; Catenin alpha-1; CTNA1_HUMAN; CTNNA 1; Ctnna1; FLJ36832; FLJ52416; MDPT2; NY REN 13 antigen; OTTHUMP00000224141; OTTHUMP00000224147; Renal carcinoma antigen NY REN 13; Renal carcinoma antigen NY-REN-13] |
Gene, Accession # | [CTNNA1], Gene ID: 1495, NCBI: NP_001277236.1, UniProt: P35221 |
Catalog # | MBS9604448 |
Price | $240, $280 |
Order / More Info | Phospho-E-Catenin (Ser655/Thr658) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |