MESDC2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | MESDC2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: MESDC2 antibody detects endogenous levels of total MESDC2. Function: Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction. Plays an essential role in neuromuscular junction (NMJ) formation by promoting cell-surface expression of LRP4 (By similarity). May regulate phagocytosis of apoptotic retinal pigment epithelium (RPE) cells (By similarity).Subunit Structure: Monomer. Interacts with LRP5; the interaction prevents LRP5 from f |
| Immunogen | Immunogen: A synthesized peptide derived from human MESDC2 Subcellular Location: Endoplasmic Reticulum. Predicted Cross Reactivity: Zebrafish, Bovine, Chicken Similarity: Zebrafish (100%), Bovine (100%), Chicken (100%) |
| Other Names | [BOCA; KIAA0081; LDLR chaperone MESD; MESD; MESD_HUMAN; MESDC 2; mesdc2; Mesoderm development candidate 2; Mesoderm development protein; Renal carcinoma antigen NY REN 61; Renal carcinoma antigen NY-REN-61] |
| Gene, Accession # | [MESDC2], Gene ID: 23184, NCBI: NP_055969.1, UniProt: Q14696 |
| Catalog # | MBS9608471 |
| Price | $240, $280 |
| Order / More Info | MESDC2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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