MEK5 (pSer311/ pThr315, Phospho-specific) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | MEK5 (pSer311/ pThr315, Phospho-specific) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat, mouse, chicken, dog |
| Isotype | n/a |
| Format | epitope affinity purified |
| Size | 0.1 mg |
| Concentration | Size: 100 ug/200 ul |
| Applications | ELISA, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody recognizes ~49 kDa of human MEK5 protein at the phosphorylation site of Ser 311/Thr315. It does not cross react to non-phospho MEK5. It also reacts with mouse and rat, chicken. The other species are not tested. The MEK5 (also known as MKK5, MAPKK5, SKK5) is a dual specificity serine/threonine protein kinase belonging to the MAP kinase kinase family. It catalyzes tyrosine phosphorylation of ERK5 whereas MEK5 itself is regulated by MEKK3. An important link between MEK5 and metastatic prostrate cancer has been demonstrated. Dual phosphorylation of Ser311 and Thr315 have been implicated in cell proliferation. |
| Immunogen | Antigen Preparation: A synthetic peptide surrounding the epitope -SIAKT- with double phosphorylation sites Ser311 and Thr315. This sequence is identical among human, rat, mouse, chicken, and dog. |
| Other Names | [Rabbit MEK5 (pSer311pThr315); MAPKK5; MEK5; MKK5; MAPK/ERK Kinase 5; SKK5.], [MAP2K5; MAP2K5; MEK5; MAPKK5; PRKMK5; HsT17454; MEK5; MKK5; PRKMK5] |
| Gene, Accession # | [MAPKK5 (MEK5) (pS311/pT315)], Gene ID: 5607, NCBI: NP_660143.1, UniProt: Q13163 |
| Catalog # | MBS462077 |
| Price | $285 |
| Order / More Info | MEK5 (pSer311/ pThr315, Phospho-specific) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Tetsuro Shishido, et al. Effects of MEK5/ERK5 Association on Small Ubiquitin-Related Modification of ERK5: Implications for Diabetic Ventricular Dysfunction After Myocardial Infarction. Circulation Research. 2008; 102:1416. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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