Human PD-L1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human PD-L1 |
| Clone | [29E.2A3] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b |
| Format | unconjugated |
| Size | 0.025 mg, 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-gamma production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, ant |
| Immunogen | n/a |
| Other Names | [B7-H1; PD-L1; Programmed cell death ligand 1; B7 homolog 1; B7-H; B7H1; PDL1; PDCD1L1; PDCD1LG1] |
| Gene, Accession # | [PD-L1], Gene ID: 29126, NCBI: NP_001254635.1, UniProt: Q9NZQ7 |
| Catalog # | MBS2556979 |
| Price | $70, $110 |
| Order / More Info | Human PD-L1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Sharpe A, et al. 2007. Nat. Immunol. 8:239. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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