RAF1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRAF1
Clone[4G4]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatunconjugated
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
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DescriptionEntrez Summary: This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD s
ImmunogenImmunogen: Purified recombinant fragment of human RAF1 expressed in E Coli.
Other Names[NS5; CRAF; Raf-1; c-Raf], [NS5; CRAF; Raf-1; c-Raf]
Gene, Accession #[RAF1], Gene ID: 5894, NCBI: AAA60247.1
Catalog #MBS476263
Price$335
Order / More InfoRAF1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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