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Antigenic Specificity | Human CD275 |
Clone | [MIH11] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.2 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | Immunohistology Frozen, Flow cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti Human CD275 antibody, clone MIH11 detects CD275, also known as ICOS ligand (inducible T cell co-stimulator ligand). CD275 is a member of the B7 family, and interaction with its receptor CD278 (ICOS) plays an important role in T cell co-stimulation and inflammatory immune reactions. CD275 is expressed on activated B-cells, monocytes and dendritic cells and is also induced on non-lymphoid tissue cells such as endothelial cells, epithelial cells and muscle cells. CD275 has an important physiological role in the reactivation of effector/memory T cells on the endothelium, thus controlling entry of immune cells into inflamed tissue. The CD278-CD275 pathway is thought to be critical in the immune response to transplants, allergies and a |
Immunogen | Immunogen: CD275 - L cells Histology Positive Control Tissue: Tonsil Fusion Partners: Spleen cells from immunised BALB/c mice were fused with cells of the P3U1 myeloma cell line. Buffer Solution: Phosphate buffered saline Target Species: Human |
Other Names | [ICOS ligand isoform b; ICOS ligand; ICOS ligand; B7 homolog 2; B7 homologue 2; B7-like protein Gl50; B7-related protein 1; transmembrane protein B7-H2 ICOS ligand; inducible T-cell co-stimulator ligand; B7 homolog 2; B7-H2; B7-like protein Gl50; B7-related protein 1; B7RP-1; CD_antigen: CD275], [ICOSLG; ICOSLG; B7H2; GL50; B7-H2; B7RP1; CD275; ICOSL; LICOS; B7RP-1; ICOS-L; B7H2; B7RP1; ICOSL; KIAA0653; B7-H2; B7RP-1] |
Gene, Accession # | [CD275], Gene ID: 23308, NCBI: NP_001269979.1, UniProt: O75144 |
Catalog # | MBS216277 |
Price | $430 |
Order / More Info | Human CD275 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |