ITGB3BP - N-terminal region Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | ITGB3BP - N-terminal region |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This is a rabbit polyclonal antibody against ITGB3BP. It was validated on Western Blot using a cell lysate as a positive control.Target Description: ITGB3BP is a transcription coregulator that can have both coactivator and corepressor functions. Isoform 1, but not other isoforms, is involved in the coactivation of nuclear receptors for retinoid X (RXRs) and thyroid hormone (TRs) in a ligand-dependent fashion. ITGB3BP acts as a transcriptional corepressor via its interaction with the NFKB1 NF-kappa-B subunit, possibly by interfering with the transactivation domain of NFKB1. It induces apoptosis in breast cancer cells, but not in other cancer cells, via a caspase-2 mediated pathway that involves mitochondrial membrane permeabilization |
| Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ITGB3BP |
| Other Names | [centromere protein R isoform 2; Centromere protein R; centromere protein R; integrin subunit beta 3 binding protein; Beta-3-endonexin; Integrin beta-3-binding protein; Nuclear receptor-interacting factor 3] |
| Gene, Accession # | [ITGB3BP], Gene ID: 23421, NCBI: NP_055103, UniProt: Q13352 |
| Catalog # | MBS3211990 |
| Price | $335 |
| Order / More Info | ITGB3BP - N-terminal region Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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