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Antigenic Specificity | CHRNA10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CHRNA10 antibody detects endogenous levels of total CHRNA10. Function: Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.Subunit Structure: Forms heterooligomeric chann |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cell Junction > Synapse > Postsynaptic Cell Membrane. Cell Membrane. Tissue Specificity: Expressed in inner-ear tissue, tonsil, immortalized B-cells, cultured T-cells and peripheral blood lymphocytes. Predicted Cross Reactivity: Pig, Bovine, Horse, Dog Similarity: Pig (100%), Bovine (100%), Horse (100%), Dog (100%) |
Other Names | [Acetylcholine receptor, neuronal nicotinic, alpha-10 subunit; ACH10_HUMAN; Alpha 10 nAChR; Cholinergic receptor nicotinic alpha 10; Cholinergic receptor, neuronal nicotinic, alpha polypeptide 10; Cholinergic receptor, nicotinic, alpha polypeptide 10; CHRNA 10; CHRNA10; NACHR alpha 10; NACHR alpha-10; NACHRA10; Neuronal acetylcholine receptor protein subunit alpha 10; Neuronal acetylcholine receptor subunit alpha-10; Nicotinic acetylcholine receptor subunit alpha 10; Nicotinic acetylcholine receptor subunit alpha-10; OTTHUMP00000013620] |
Gene, Accession # | [CHRNA10], Gene ID: 57053, NCBI: NP_001289963.1, UniProt: Q9GZZ6 |
Catalog # | MBS9605693 |
Price | $240, $280 |
Order / More Info | CHRNA10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |