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Antigenic Specificity | NKG2D Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, ratpredicted reactivity: human |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: NKG2D is encoded by KLRK1 gene which is located in the NK-gene complex (NKC) situated on and chromosome 12 in humans. Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. This gene encodes a member of the NKG2 family. The encoded transmembrane protein is characterized by a type II membrane ori |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence of human NKG2D (YQFFDESKNWYESQASCMSQNASLLKVYSKEDQDLLKLVKSYH). Subcellular Localization: Cell membrane. Tissue Specificity: Expressed in natural killer (NK) cells, CD8( ) alpha-beta and gamma-delta T-cells. Expressed on essentially all CD56 CD3- NK cells from freshly isolated PBMC. Expressed in interferon-producing killer dendritic cells (IKDCs). |
Other Names | [NKG2-D type II integral membrane protein; Killer cell lectin-like receptor subfamily K member 1; NK cell receptor D; NKG2-D-activating NK receptor; CD314; KLRK1; D12S2489E; NKG2D] |
Gene, Accession # | [NKG2D], Gene ID: 100528032, NCBI: NP_001186734.1, UniProt: P26718 |
Catalog # | MBS1750460 |
Price | $280 |
Order / More Info | NKG2D Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |