Human CD209: Low Endotoxin Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CD209: Low Endotoxin
Clone[MR-1]
Host SpeciesMouse
Reactive Speciesn/a
IsotypeIgG1
Formatunconjugated
Size0.5 mg
ConcentrationIgG concentration 1.0 mg/ml
ApplicationsFlow cytometry (FC/FACS), Functional Assays (FN), Immunofluorescence (IF)
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DescriptionMouse anti Human CD209 antibody, clone MR-1 recognizes human DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN), a 45kD C-type lectin that binds ICAM-3 also known as CD209. CD209 is primarily expressed on a population of immature dendritic cells in peripheral tissues and on immature myeloid monocyte-derived DC's in vitro.CD209 is involved in dendritic cell (DC) migration and the initial interaction between DC's and naive T lymphocytes. CD209 also binds HIV-1 gp120 and plays a key role in the dissemination of HIV-1 by DC's. Clone MR-1 is reported to partially block the functional activity of DC-SIGN (Melero et al.).
Immunogenn/a
Other Names[CD209 antigen isoform 5; CD209 antigen; CD209 antigen; C-type lectin domain family 4 member L; C-type lectin domain family 4, member L; HIV gpl20-binding protein; dendritic cell-specific ICAM-3-grabbing non-integrin 1; dendritic cell-specific intracellular adhesion molecules (ICAM)-3 grabbing non-integrin; CD209 molecule; C-type lectin domain family 4 member L; Dendritic cell-specific ICAM-3-grabbing non-integrin 1; DC-SIGN; DC-SIGN1; CD_antigen: CD209], [CD209; CD209; CDSIGN; CLEC4L; DC-SIGN; DC-SIGN1; CLEC4L; DC-SIGN; DC-SIGN1]
Gene, Accession #[CD209], Gene ID: 30835, NCBI: NP_001138365.1, UniProt: Q9NNX6
Catalog #MBS211234
Price$675
Order / More InfoHuman CD209: Low Endotoxin Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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