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Antigenic Specificity | Human CD209: Low Endotoxin |
Clone | [MR-1] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.5 mg |
Concentration | IgG concentration 1.0 mg/ml |
Applications | Flow cytometry (FC/FACS), Functional Assays (FN), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti Human CD209 antibody, clone MR-1 recognizes human DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN), a 45kD C-type lectin that binds ICAM-3 also known as CD209. CD209 is primarily expressed on a population of immature dendritic cells in peripheral tissues and on immature myeloid monocyte-derived DC's in vitro.CD209 is involved in dendritic cell (DC) migration and the initial interaction between DC's and naive T lymphocytes. CD209 also binds HIV-1 gp120 and plays a key role in the dissemination of HIV-1 by DC's. Clone MR-1 is reported to partially block the functional activity of DC-SIGN (Melero et al.). |
Immunogen | n/a |
Other Names | [CD209 antigen isoform 5; CD209 antigen; CD209 antigen; C-type lectin domain family 4 member L; C-type lectin domain family 4, member L; HIV gpl20-binding protein; dendritic cell-specific ICAM-3-grabbing non-integrin 1; dendritic cell-specific intracellular adhesion molecules (ICAM)-3 grabbing non-integrin; CD209 molecule; C-type lectin domain family 4 member L; Dendritic cell-specific ICAM-3-grabbing non-integrin 1; DC-SIGN; DC-SIGN1; CD_antigen: CD209], [CD209; CD209; CDSIGN; CLEC4L; DC-SIGN; DC-SIGN1; CLEC4L; DC-SIGN; DC-SIGN1] |
Gene, Accession # | [CD209], Gene ID: 30835, NCBI: NP_001138365.1, UniProt: Q9NNX6 |
Catalog # | MBS211234 |
Price | $675 |
Order / More Info | Human CD209: Low Endotoxin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |