Mouse CD86 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse CD86
Clone[GL-1]
Host SpeciesRat
Reactive Speciesmouse
IsotypeIgG2a
Formatunconjugated
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
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DescriptionCD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
Immunogenn/a
Other Names[Mouse CD86; T-lymphocyte activation antigen CD86; Cd86; Activation B7-2 antigen; Early T-cell costimulatory molecule 1; ETC-1]
Gene, Accession #[CD86], Gene ID: 12524, NCBI: NP_062261.3, UniProt: P42082
Catalog #MBS2553713
Price$75, $90
Order / More InfoMouse CD86 Antibody from MYBIOSOURCE INC.
Product Specific References1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press. 2. Hathcock KS, et al. 1993. Science 262:905. 3. Freeman GJ, et al. 1993. Science 262:907. 4. Carreno BM, et al. 2002. Annu. Rev. Immunol. 20:29.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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