DNA Polymerase alpha Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDNA Polymerase alpha
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous levels of total DNA Polymerase a protein. Plays an essential role in the initiation of DNA replication. During the S phase of the cell cycle, the DNA polymerase alpha complex (composed of a catalytic subunit POLA1/p180, a regulatory subunit POLA2/p70 and two primase subunits PRIM1/p49 and PRIM2/p58) is recruited to DNA at the replicative forks via direct interactions with MCM10 and WDHD1. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. These primers are initially extended by the polymerase alpha catalytic subunit and subsequently transferred to polymerase delta and polymerase epsilon for processive synthesis on
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from N-terminal of human DNA Polymerase a.
Other Names[DNA Polymerase a; DNA pol alpha; DNA polymerase alpha catalytic subunit; DPOA; DPOLA; EC 2.7.7.7]
Gene, Accession #Gene ID: 5422, NCBI: NP_058633.2, UniProt: P09884
Catalog #MBS9413092
Price$200, $255
Order / More InfoDNA Polymerase alpha Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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