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Antigenic Specificity | Human Granzyme B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | fluorescein (FITC) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis. |
Immunogen | Immunogen: Recombinant human Granzyme B protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-1968 / sc-1969 |
Other Names | [C11; CTLA-1; Cathepsin G-like 1; CTSGL1; Cytotoxic T-lymphocyte proteinase 2; Lymphocyte protease; Fragmentin-2; Granzyme-2; Human lymphocyte protein; HLP; SECT; T-cell serine protease 1-3E; GZMB; CGL1; CSPB; CTLA1], [GZMB; GZMB; HLP; CCPI; CGL1; CSPB; SECT; CGL-1; CSP-B; CTLA1; CTSGL1; CGL1; CSPB; CTLA1; GRB; CTSGL1; Lymphocyte protease; HLP] |
Gene, Accession # | [GRB], Gene ID: 3002, NCBI: NP_004122.2, UniProt: P10144 |
Catalog # | MBS1488980 |
Price | $160, $235 |
Order / More Info | Human Granzyme B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |