HNMT Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHNMT
Clone[432CT31.4.2]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatascites
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: Purified His-tagged HNMT protein(Fragment) was used to produced this monoclonal antibody. In mammals, histamine is metabolized by two majorpathways: N(tau)-methylation via histamine N-methyltransferase andoxidative deamination via diamine oxidase. This gene encodes thefirst enzyme which is found in the cytosol and usesS-adenosyl-L-methionine as the methyl donor. In the mammalianbrain, the neurotransmitter activity of histamine is controlled byN(tau)-methylation as diamine oxidase is not found in the centralnervous system. A common genetic polymorphism affects the activitylevels of this gene product in red blood cells. Multiplealternatively spliced transcript variants that encode different
Immunogenn/a
Other Names[Histamine N-methyltransferase; HMT; HNMT]
Gene, Accession #[HNMT], Gene ID: 3176, NCBI: NP_001019245.1, UniProt: P50135
Catalog #MBS9200455
Price$370
Order / More InfoHNMT Antibody from MYBIOSOURCE INC.
Product Specific ReferencesStevenson, J., et al. Am J Psychiatry 167(9):1108-1115(2010) Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Schuurhof, A., et al. Pediatr. Pulmonol. 45(6):608-613(2010) Davila, S., et al. Genes Immun. 11(3):232-238(2010)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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