RB1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRB1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.1 mL
Concentration2.1 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous levels of total RB1 protein. The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma
ImmunogenImmunogen Type: Recombinant Protein Immunogen Description: Fusion protein corresponding to residues near the C terminal of human retinoblastoma 1
Other Names[RB; pRb; OSRC; pp110; p105-Rb]
Gene, Accession #[RB1], Gene ID: 5925, NCBI: NP_000312.2, UniProt: P06400
Catalog #MBS9411876
Price$255
Order / More InfoRB1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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