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Antigenic Specificity | RBBP8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | RBBP8, also known as CtBP (carboxy-terminal binding protein) interacting protein (CTIP), was characterized for its role in transcription as a cofactor for the transcriptional repressor CtBP, and also as a binding partner for other proteins including the cell cycle regulators retinoblastoma protein (Rb) and breast cancer 1 (BRCA1). It is ubiquitously expressed and localizes to the nucleus. RBBP8 is thought to modulate the functions in cell proliferation, transcriptional regulation and DNA repair. RBBP8 also plays a central role in the cell cycle checkpoint response to DNA double-stranded breaks (DSBs), with new evidence demonstrating that it controls the choice of DSB repair pathway. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 14 amino acid peptide near the center of human RBBP8. |
Other Names | [Retinoblastoma-binding protein 8, CTIP, CtBP-interacting protein, RIM] |
Gene, Accession # | [RBBP8], Gene ID: 5932, NCBI: NP_976037 |
Catalog # | MBS9411781 |
Price | $320 |
Order / More Info | RBBP8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |