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Antigenic Specificity | FAAH |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: FAAH antibody detects endogenous levels of total FAAH. Description: Endogenous cannabinoids have been implicated in addictive behaviors and drug abuse (1). Fatty-acid amide hydrolase 1 (FAAH1) is a plasma membrane-bound hydrolase that converts oleamide to oleic acid (2). This hydrolase also converts the cannabinoid anandamide, the endogenous ligand for the CB1 cannabinoid receptor, to arachidonic acid, suggesting a role in fatty-acid amide inactivation (2). Mice lacking FAAH1 have significantly higher levels of anandamide in the brain and show decreased sensitivity to pain, further indicating a role for FAAH1 in the regulation of endocannabinoid signaling in vivo (3). FAAH1 null mice also demonstrate an increased preference for |
Immunogen | Immunogen: A synthesized peptide derived from human FAAH Subcellular Location: Endomembrane System. Cytoplasm > Cytoskeleton. Seems to be attached to intracellular membranes and a portion of the cytoskeletal network. Tissue Specificity: Highly expressed in the brain, small intestine, pancreas, skeletal muscle and testis. Also expressed in the kidney, liver, lung, placenta and prostate. Predicted Cross Reactivity: Pig, Horse, Rabbit, Dog Similarity: Pig (88%), Ho |
Other Names | [Anandamide amidohydrolase 1; Anandamide amidohydrolase; FA2H; FAAH; FAAH-1; FAAH1_HUMAN; Fatty acid 2-hydroxylase; Fatty acid alpha-hydroxylase; Fatty acid amide hydrolase; Fatty-acid amide hydrolase 1; MGC102823; MGC138146; Oleamide hydrolase 1; Oleamide hydrolase] |
Gene, Accession # | [FAAH], Gene ID: 2166, NCBI: NP_001432.2, UniProt: O00519 |
Catalog # | MBS9606967 |
Price | $240, $280 |
Order / More Info | FAAH Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |