HDAC6 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-HDAC6 antibody, protein, ELISA kits.
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|---|---|
| Antigenic Specificity | HDAC6 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | HDAC6 is a class II histone deacetylase enzyme localized to the cytoplasm and associated with the microtubule network (1). It is involved in the regulation of many cellular processes, including cell migration, immune synapse formation, viral infection, and degradation of misfolded proteins (1). HDAC6 contains two tandem catalytic domains that facilitate the deacetylation of multiple protein substrates, including histones and non-histone proteins such as tubulin, cortactin, and HSP90. Despite the ability to deacetylate histone proteins in vitro, there is no evidence for HDAC6-mediated deacetylation of histones in vivo (2, 3). The acetylation/deacetylation of tubulin on Lys40 regulates binding and motility of the kinesin-1 motor protein and s |
| Immunogen | Immunogen: Recombinant protein of human HDAC6 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [FLJ16239; HD6; JM21] |
| Gene, Accession # | [HDAC6], Gene ID: 10013, NCBI: NP_001308155.1, UniProt: Q9UBN7 |
| Catalog # | MBS8503558 |
| Price | $310 |
| Order / More Info | HDAC6 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Boyault, C. et al. (2007) Oncogene 26, 5468-76. 2. Haggarty, S.J. et al. (2003) Proc Natl Acad Sci U S A 100, 4389-94. 3. Zhang, Y. et al. (2003) EMBO J 22, 1168-79. 4. Reed, N.A. et al. (2006) Curr Biol 16, 2166-72. 5. Zhang, X. et al. (2007) Mol Cell 27, 197-213. 6. Kovacs, J.J. et al. (2005) Mol Cell 18, 601-7. 7. Murphy, P.J. et al. (2005) J Biol Chem 280, 33792-9. 8. Seigneurin-Berny, D. et al. (2001) Mol Cell Biol 21, 8035-44. 9. Kawaguchi, Y. et al. (2003) Cell 115, 727-38. 10. Boyault, C. et al. (2006) EMBO J 25, 3357-66. 11. Iwata, A. et al. (2005) J Biol Chem 280, 40282-92. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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