PRKCI Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPRKCI
Clone[3A1B6]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG2a
FormatProtein A purified
Size0.06 mL, 0.12 mL, 0.2 mL
Concentration1mg/mL
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThe atypical protein kinase C isoform PRKC iota (PRKCI) is a member of the protein kinase C (PKC) family of serine/threonine protein kinases. PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. PRKC iota is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-in
ImmunogenImmunogen: Fusion protein of PKC iota
Other Names[PKC iota; aPKC lambda/iota; aPKC-lambda/iota; Atypical protein kinase C lambda/iota; Atypical protein kinase C-lambda/iota; DXS1179E; KPCI; MGC26534; nPKC iota; nPKC-iota; nPKCiota; PKC lambda; PKC lambda/iota; PKCI; PKCiota; PKClambda; PRKC iota; PRKC lambda/iota; PRKC-lambda/iota; PRKCI; Protein kinase C iota; Protein kinase C iota type]
Gene, Accession #[PRKCI], Gene ID: 5584, NCBI: NP_002731.4, UniProt: P41743
Catalog #MBS2549123
Price$220, $290, $435
Order / More InfoPRKCI Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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